The national peak body for Aboriginal Community-Controlled Health Organisations has voted overwhelmingly in favour of adopting a new constitution.

At a meeting on Kaurna Country on Wednesday, over 80 per cent of members of the National Aboriginal Community-Controlled Health Organisation (NACCHO), the peak body representing 146 ACCHOs nationwide, voted for a model change.

NACCHO Chair Donnella Mills said the significance of the change could not be overstated, arguing it reflected the "strength and unity" of NACCHO's membership, as well as their "commitment to community control".

"We appreciate everyone who contributed to the consultations and voting process," Ms Mills said.

"A constitution should be dynamic, but most importantly, I am pleased that we now have a modern constitution that will equip us to meet current challenges more effectively."

NACCHO had argued the previous constitution was outdated, noting they often had to seek legal advice to "resolve what should be straightforward questions".

Furthermore, there were criticisms of its convoluted nature.

As such, the new constitution is less than half the length, at 32 pages, and in "plain English".

Chief executive Pat Turner said the changes were a major step forward, with the strong endorsement by members a "testament to our sector's commitment to self-determination".

"It is difficult to think of a more consultative and ground-up process," Ms Turner said.

"Since 2016, when the process began, we have spoken to over 1,000 people, held almost 60 sessions and meetings, run workshops all over the country, surveys, and webinars. It demonstrates the resilience of our sector and co-design."

NACCHO members stayed in Adelaide on Thursday to help the Board develop a new strategic directions plan to offer up the sector's priorities before the upcoming preliminary term begins.

"We are now positioned better than ever as a sector to meet the challenges ahead and become an even more powerful voice for our peoples," Ms Mills said.