Manly's woes have deepened in the wake of prop Toff Sipley being referred directly to the judiciary for a hip-drop tackle on St George Illawarra winger Mat Feagai.
The incident, which drew a dangerous contact charge, took place in the 53rd minute of the Sea Eagles' disappointing 20-18 loss at 4 Pines Park on Thursday night.
Feagai was assisted from the field by two trainers and did not return. He will go for scans on a possible serious leg injury that could sideline him long-term.
Sipley was sin-binned and put on report and also left the field for an HIA after the tackle.
Sea Eagles captain Daly Cherry-Evans said post-match Sipley "might have been concussed and then lost his legs" while making the tackle.
"It looks pretty accidental from what I saw," he said.
Manly had their misery compounded during the match with Samoan centre/winger Tommy Talau (leg), as well as Nathan Brown (shoulder) and Jake Trbojevic (concussion).
The trio are expected to miss the round-eight clash with Penrith.
The Sea Eagles have now lost their last three matches to slide out of the top eight after being second in round four.
Joe Gould - AAP