About 20,000 people met on Meanjin land on Thursday to hit the streets and stand in solidarity against "Australia Day" which commemorates the genocide of First Nations people.

Despite the sweltering heat, Meanjin showed huge support in attendance and in spirit for the ongoing battle the First Nations people have faced for more than 200 years.

Many speakers and activists took to the stage to share stories and songs, speak out against police brutality, empower Indigenous people, and pay respects to those who have fought and fallen for the rights of First Nations people.

Beginning at Queens Gardens in Meanjin/Brisbane CBD, the march passed over the William Jolly Bridge, through South Brisbane before ending at Musgrave Park; a significant meeting place for Meanjin's First Nations communities.

Speeches were kept short due to the heat but Uncle Wayne Wharton managed to get the crowd going with his usual emphatic delivery and unapologetic wording during his speech.

"You're either an accomplice, or an ally," he said.

"In the words of Robbie Thorpe, Australia is a crime scene."

Other community Elders also took to the stage to share their thoughts.

"Today I can sense the energy of our old ones from the past and know that when we march to our meeting place in Musgrave Park, I will hear their voices singing," said a community Elder.

"Today as we express our voices, to our Brisbane Black community - I ask everyone to pay respects to our old people.

"Today I say thank you to the families who, like myself, always had our kids beside us in the fight for justice," she said.

The streets of Meanjin were echoing with chants such as;

"No justice - no peace, no racist police"

"Always was, always will be, Aboriginal Land"

"How do you spell racist? Q-P-S"

"We demand our stolen land, The Voice is a sham"

Upon arriving at Musgrave Park, marchers were met with music by local First Nations artists and food and drinks.

Invasion day protests were carried out in major cities and towns throughout the country.