Opposition leader Peter Dutton has acknowledged the resignation of Julian Leeser and noted Leeser is a "man of great character, of strength".

His comments come after the Shadow Attorney-General and Shadow Minister for Indigenous Australians quit the Liberal front bench after citing personal opposition to the party's "no" stance on a constitutionally enshrined Indigenous Voice to Parliament.

In a press conference shortly after his resignation, Mr Dutton said Mr Leeser is a person with the country's best interest at heart.

"...As he pointed out, he doesn't leave with rank or he doesn't leave with bitterness, he has gone through a process within our party," he said.

"He has gone through a process in our party and his position is at odds with the overwhelming majority of the Liberal Party members in our party room.

"So our determination is to make sure we have local and regional voices because we want to listen to those people in the communities and get the best possible outcome for them.

"The prime minister's proposal which is a Canberra voice, is not going to deliver that outcome."

Both Mr Dutton and Mr Leeser noted the latter was resigning in a respectful manner.

Mr Dutton emphasised his issue is with Prime Minister Anthony Albanese's wording on the Voice and the need for a local and regional Voice before a national Voice.

"As he (Leeser) pointed out today, he's campaigning now to see the prime minister change the words," Mr Dutton said.

"The PM has changed the words three times already or twice from the original version so there are three forms of words out there."

The Calma-Langton report was referenced multiple times with an emphasis placed on its calls for a local and regional Voice first.

Mr Dutton said he and Mr Leeser were on the same page about a local and regional Voice.

"Since May of last year, the prime minister hasn't been involved us in those tangible discussions, and in Calma-Langton (report) that the prime minister made multiple references to," Mr Dutton said.

"It talks there about having a local and regional arrangement before you go to a national voice. We have agreed with that position.

"Prime minister is now at odds with that advice."

It comes a week after co-author of the report Marcia Langton accused Mr Dutton on ABC 7.30 as being deceitful.

"I think his opposition to the Voice relies absolutely on deceit and misrepresentations. And, and I have to say, a great deal of ignorance," she said.

"He wants to sow confusion and doubt, so that the undecided people and the people who are wavering, because they're starting to think 'yeah, I haven't seen any detail' … they think that he's able to, you know, swing them to a no vote to secure what he believes is his constituency."

However Mr Dutton noted it was the prime minister who was dividing the country.

"I point out in Julian's statement this morning his criticism of the approach taken by the prime minister," Mr Dutton said.

"If anybody in this debate is dividing the country, it's Anthony Albanese."