The federal government is set to announce $100 million worth of support for 33 Indigenous health infrastructure projects across the country.

The announcement, occurring at a Joint Council on Closing the Gap meeting on Kaurna Country on Friday, will see investment go towards the construction of new health clinics, as well as renovating existing ones and constructing housing for workers.

Assistant Minister for Indigenous Health, Malarndirri McCarthy, said the government was committed to strengthening the Aboriginal community-controlled health sector.

"Roughly half of all First Nations people receive their medical care through an ACCHS [Aboriginal Community Controlled Health Services], so it is essential that these clinics are fit for purpose," Senator McCarthy said.

"Ensuring health workers have access to accommodation will help ACCHS to hire and keep staff, resulting in greater access to health care services for First Nations people."

The grants were co-designed with the National Aboriginal Community Controlled Health Organisation (NACCHO) on behalf of the ACCHS sector.

The announcement comes as the government is pressured by Aboriginal Community-Controlled Health Organisations (ACCHO) to embrace self-determination in healthcare after a scathing productivity commission report earlier this year found progress to implement the National Agreement Closing the Gap (National Agreement) reforms were "weak".

Minister for Indigenous Australians, Lina Burney, said her government was committed to closing the gap in health care, and said the new upgrades to clinics would make it easier for First Nations people to access "primary health care".

"ACCHS provide crucial medical care and are often the only health service available in rural and remote communities," Ms Burney said.

NACCHO chief executive and lead convener of the Coalition of Peaks, Pat Turner, said she was pleased the funding was being delivered in line with the National Agreement, and in genuine partnership with ACCHOs.

"This funding supports the critical role that ACCHOs play and the contribution they make every day in improving health outcomes for our people," Ms Turner said.

"The infrastructure funding need in our sector remains a critical pressure-point and NACCHO will continue to advocate for increased funding for our sector."

Many of the existing ACCHS' buildings and clinics are ageing — some up to 40 years old.

Ms Turner said the flailing infrastructure could compromise the delivery of healthcare, as well as posing a risk to patients and staff, and act as a deterrent for future staff seeking employment.

"The Government's injection of $100 million is a welcome support for those services under funding pressures to better serve their communities," she said.