An Aboriginal woman has died in custody in Tasmania, the state's prison director has confirmed.

The prisoner, reported to have been on remand, died on Monday, with no further details of the incident so far released.

On Tuesday, Tasmanian Aboriginal Legal Service CEO Jake Smith said the loss of life "will profoundly impact her family, the community and others across Lutruwita/Trouwunna/Tasmania".

"TALS stands ready to support the family and community during this difficult time," Mr Smith said.

"It is with great sadness that we have seen an Aboriginal death in custody here in Tasmania.

"The impact of this loss will be felt by community for some time."

Following the death, Mr Smith reiterated Aboriginal people in Tasmania remain overrepresented in custody, being five times more likely to be in imprisoned than non-Aboriginal people.

"TALS and many others have long advocated for meaningful change," he said.

"While it is too early to comment on the circumstances surrounding this tragic event, it is a reminder of the urgent need for culturally safe and effective justice systems."

Tasmanian director of prisons, Narelle Pamplin, said in a statement on Tuesday: "On behalf of the Tasmania Prison Service I extend my sincere condolences to the family and friends of the deceased woman at this difficult time," the ABC reports.

"The Tasmania Prison Service will not be making any further comment as the matter will now be referred to the coroner for examination."

Mr Smith said TALS is urging the Tasmanian Government to engage respectfully and transparently with the family and broader community "and to ensure open and ongoing dialogue to help prevent further tragedies".