The stagnating and declining progress across critical Closing the Gap targets has real consequences for First Nations people, a new report says.

The Productivity Commission's latest Closing the Gap data, published last week, revealed progress in some key areas across states and territories, but critical targets requiring urgent government action - particularly in suicide prevention, incarceration, and child removal – had worsened.

On Thursday, a report by The Close the Gap (CTG), an independent, Indigenous-led campaign made up of 53 Indigenous and non-Indigenous health, NGOs, and human rights organisations, offered "tangible solutions to close the gap" with the themes of "Agency and Self-determination", "Leadership and Solidarity", and "Reform and Transformation".

Underpinned by the United Nations Declaration on the Rights of Indigenous Peoples (UNDRIP), it noted the only way to close the gap was by "creating genuine systemic reform".

Co-chair of Close the Gap - who are not affiliated with the Australian Government Closing the Gap Strategy - and Aboriginal and Torres Strait Islander Social Justice Commissioner, Katie Kiss, stressed the significance of holding governments accountable for their commitments.

"A critical element of our report is to demonstrate that genuine reform for the betterment of Aboriginal and Torres Strait Islander peoples must be grounded in our rights as First Peoples," she said.

"Our respect for and desire to protect our lands, seas, and cultures shapes who we are and how we exist in the world. It permeates our being and drives the initiatives we put forth to ensure the survival, dignity, and wellbeing of our peoples."

Ms Kiss said the recommendations in the report were "clear," and noted the report highlighted the importance of building an enabling and supportive environment at the departmental and agency level, which in turn would allow the Closing the Gap targets to be achieved at a local level.

"Through their collective efforts, Aboriginal and Torres Strait Islander peoples have made meaningful strides," Commissioner Kiss said.

"However, there is still much more to be done to ensure that the health and wellbeing of First Nations peoples are truly prioritised."

Amongst the report's 44 recommendations, it called for a full implementation of the 2024 Closing the Gap Review; establish a national framework to deliver Voice, Truth and Treaty; establish a body to monitor the recommendations from the Royal Commission into deaths in custody; and implement all the recommendations from the National Children's Commissioner's report: Help Way Earlier!

"This campaign, our work, is about amplifying and championing Aboriginal and Torres Strait Islander-led solutions and showing how our leadership is the key to achieving genuine, sustainable reform," fellow co-chair, Karl Briscoe, said.

"This campaign, our work, is about amplifying and championing Aboriginal and Torres Strait Islander-led solutions and showing how our leadership is the key to achieving genuine, sustainable reform."

The report also focussed on the success of First Nations leaders actively "shaping solutions and paving the way to close the gap".

Commissioner Kiss said the National Agreement on Closing the Gap was a "landmark policy initiative" aimed at delivering improved outcomes across the country in several key metrics.

"All state and territory governments have signed onto the National Agreement, and they must be held accountable for its implementation," she said.