The inaugural South Australian Voice to Parliament has taken its a key step, meeting for the first time to appoint its presiding members.

Legislated to give advice to the state's parliament, government and other key-decision makers on issues that affect and impact Indigenous people, the body held its first formal meeting on Kaurna Country this week.

It is made up of 12 First Nations people representing six regions across the state, and they will guide the Voice's efforts to ensure it aligns to First Nations' community priorities.

Narungga, Kaurna and Ngarrindjeri woman Tahlia Wanganeen, representing metropolitan Adelaide First Nations communities, and a Marlinyu Ghoorlie, Wirangu, Kokatha, Mirning, Noongar and Barngala man Leeroy Bilney from the far west coast, were chosen to lead the advisory body.

"The establishment of this State Voice represents a vital step forward for community by ensuring that the decisions that impact Aboriginal and Torres Strait Islander people reflect the true needs of our communities based on our lived experiences," Ms Wanganeen said.

"I am honoured to be elected to this important position by my community and now my peers on the State Voice.

"It is a big task, but we can do this together."

Mr Bilney said the body was committed to bringing the voices of First Nations communities across South Australia to the government.

"So that they are hearing directly from our communities and from people who may not have had a chance to share their views on matters that they care about deeply," he said.

The inaugural elections earlier this year saw 113 candidates compete for 46 seats across the six local Voice regions. Of those 46 positions, 12 of the First Nations representatives have now been selected as presiding members.

The body is not enshrined in the state's constitution, rather legislated by parliament.

SA Minister for Aboriginal Affairs, Kyam Maher, said the meeting was an historic day for the state, and said Indigenous people in South Australia "expect a strong, independent Voice to advocate on their behalf" to government, parliament, and the chief executive of agencies.

"Each of the 12 Local Voice presiding members are respected committed leaders who I know will be steadfast in representing their Aboriginal communities and help us, as Parliamentarians and decision makers, make better and more informed decisions that will strengthen our state," he said.

"I congratulate the members of the State Voice and its two newly elected presiding members, and I look forward to working with them as we collectively embark on this historic journey."