Brisbane defender Keidean Coleman has hit a speed bump in his AFL comeback and is one of three Lions players to join a lengthy injury list.

Coleman could be ruled out for up to six weeks after straining his hamstring just before quarter-time in the club's 25-point loss to Fremantle.

The 26-year-old has played all 12 games this season after missing Brisbane's back-to-back premierships.

Coleman had suffered a season-ending ACL tear in opening round in 2024, then played just one AFL game last year before a quad strain.

Elsewhere, in-form defender Lawson Humphries is in doubt for Geelong's away clash with Adelaide.

The 23-year-old had landed awkwardly after a contest for the ball with Carlton opponent Flynn Young in the club's eventual four-point loss to the Blues.

"They were pretty optimistic afterwards, in the immediate aftermath," Geelong coach Chris Scott said.

"We've taken an attitude that we would like to shift the idea that it's possible players play, so can they play, to more of a conversation around should they play.

"It puts a bit of doubt on Lawson, but it shouldn't be construed as he couldn't play."

Scott confirmed veteran Jack Martin will return against Adelaide after he was rested against the Blues.

Australian Associated Press