The final days of the Yoorrook Justice Commission heard experts expose the significantly higher risk Indigenous women and children face in custody.

Curtin University professor within the Faculty of Health Sciences, Stuart Kinner, said the vast gap in the safety and wellbeing statistics called for better health-based strategies.

"There's a desperate need for greater support...what we now know increasingly is that a lot of women that we see at risk after release from prison were at risk before they went to prison in the first place," Mr Kinner said.

"Sending people to prison is not a solution to any of those risks, but not sending them to prison in and of itself is not sufficient to mitigate those risks."

According to Indigenous experts, Indigenous women are 13 times at greater risk of death after being released from prison.

Additionally, Indigenous children make up 60 to 70 per cent of incarcerated children.

University of Melbourne associate dean of Indigenous programs, Eddie Cubillo, said during the commission's hearings that children's lives are at risk.

"Aboriginal people are always talking about these things, giving evidence and getting nothing," he said.

"Aboriginal people have a lot at stake when engaging in this kind of advocacy. It's not a game for us, it's our family and our kids' lives that are at stake."

The Victorian Aboriginal Legal Service appeared before the Yoorrook Justice Commission to call for radical change for First Nations people in Victoria.

VALS called for standalone child protection legislation for Aboriginal children and families.

Victoria has the highest rate of Aboriginal child removal in the country.

Aboriginal children are also more than eight times more likely than non-Aboriginal children to be the subject of a child protection substantiation in Victoria.

As a result of the Yoorrook Justice Commission, VALS is urging the Victorian government to make urgent changes to the criminal justice system.

VALS executive officer Nerita Waight said the criminal justice systems is immersed within a colonial history.

"Aboriginal people are telling our truths. At Yoorrook, witnesses and Commissioners have been in tears with the pain of reliving those stories. Is the Premier listening?" she said.

"Daniel Andrews was eager to make commitments about child protection, and we will work with him and Aboriginal communities to make it happen.

"Now he needs to make the same kind of commitment to transform Victoria's unjust criminal legal system, and end Aboriginal deaths in custody, before another 30 years pass without any change."

A Victorian government spokesperson said they are looking forward to the Commission handing down its recommendations so they can continue to work towards Treaty.

"Only by reconciling with the past, and its impact to this very day, can we achieve a fairer more just future for Aboriginal Victorians - because without truth, there can be no Treaty - and without Treaty, there can be no justice," they said.

"We know that more needs to be done to address the over-representation of Aboriginal Victorians in the child protection and justice systems - that's why we're implementing a range of reforms with self-determination at their core."